ABO blood groups and risk of deep venous thromboembolism in Chinese Han population from Chaoshan region in South China

Min Yu, Cantian Wang, Tingting Chen, Shuang Hu, Kaihong Yi, Xuerui Tan

Abstract


 Objectives: To demonstrate the prevalence of ABO blood groups with deep venous thromboembolism in Chinese Han population.

Methods: A retrospective study was conducted between January 2010 and March 2015 in The First Affiliated Hospital of Shantou University Medical College in Chaoshan District of Guangdong Province in South China. Eighty nine patients with confirmed diagnosis of deep venous thromboembolism were included. Frequency of blood groups was determined. 

Results: Of 89 patients with deep venous thromboembolism, 28 patients had blood group A (31.5%), 28 patients had blood group B (31.5%), 13 patients had blood group AB (14.6%), and 20 patients had blood group O (22.5%). Compared with O blood type, the odds ratios of deep venous thromboembolism for A, B and AB were 2.23 (95% CI, 1.27-3.91), 2.34 (95% CI, 1.34-4.09) and  4.43 (95% CI, 2.24-8.76). 

Conclusion: There is a higher risk of venous thromboembolism in non-O blood groups than O group.

 

Saudi Med J 2017; Vol. 38 (4): 396-399

doi: 10.15537/smj.2017.4.16349


How to cite this article:

Yu M, Wang C, Chen T, Hu S, Yi K, Tan X. ABO blood groups and risk of deep venous thromboembolism in Chinese Han population from Chaoshan region in South China. Saudi Med J. 2017 Apr;38(4):396-399. doi: 10.15537/smj.2017.4.16349.



Keywords


Deep venous thromboembolism; ABO Blood Group; Risk factor

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References


Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med 1991; 151: 933-938.

Oger E. Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBP Study Group. Thromb Haemost. 2000; 83: 657-660.

Cheuk BL, Cheung GC, Cheng SW. Epidemiology of venous thromboembolism in a Chinese population. Br J Surg 2004; 91: 424-428.

Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, et al. Prevention of venous thromboembolism:American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133 (6 Suppl): 381S–453S.

Clark P, Wu O. ABO blood groups and thrombosis: A causal association, but is there value in screening? Future Cardiol 2011; 7: 191-201.

Spiezia L, Campello E, Bon M, Tison T, Milan M, Simioni P, et al. ABO blood groups and the risk of venous thrombosis in patients with inherited thrombophilia. Blood Transfus 2013; 11: 250-253.

Gallerani M, Reverberi R, Manfredini R. ABO blood groups and venous thromboembolism in a cohort of 65,402 hospitalized subjects. Eur J Intern Med 2014; 25: e27-e28.

Vasan SK, Rostgaard K, Majeed A, Ullum H, Titlestad KE, Pedersen OB, et al. ABO Blood Group and Risk of Thromboembolic and Arterial Disease: A Study of 1.5 Million Blood Donors. Circulation 2016; 133: 1449-1457.

Huang L, Huang R. ABO blood groups distribution in the population of in the East of Guangdong. Journal of Shantou University Medical College 1995; 1: 92-92. [Chinese]

Jick H, Slone D, Westerholm B, Inman WH, Vessey MP, Shapiro S, et al. Venous thromboembolic disease and ABO blood type. A cooperative study. Lancet 1969; 1: 539-542.

Wolpin BM, Kabrhel C, Varraso R, Kraft P, Rimm EB, Goldhaber SZ, et al. Prospective study of ABO blood type and the risk of pulmonary embolism in two large cohort studies. Thromb Haemost 2010; 104: 962-971.

Larsen TB, Johnsen SP, Gislum M, Møller CAI, Larsen H, Sørensen HT. ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case–control study. J Thromb Haemost 2005; 3: 300-304.

El-Galaly TC, Kristensen SR, Overvad K, Steffensen R, Tjønneland A, Severinsen MT. Interaction between blood type, smoking and factor V Leiden mutation and risk of venous thromboembolism: a Danish case-cohort study. J Thromb Haemost 2012; 10: 2191-2193.

Sode BF, Allin KH, Dahl M, Gyntelberg F, Nordestgaard BG. Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type. CMAJ 2013; 185: E229-E237.

Suchon P, Al Frouh F, Henneuse A, Ibrahim M, Brunet D, Barthet MC, et al. Risk factors for venous thromboembolism in women under combined oral contraceptive. The PILl Genetic Risk Monitoring (PILGRIM) Study. Thromb Haemost 2016; 115: 135-142.

Mizrahi T, Leclerc JM, David M, Ducruet T, Robitaille N. ABO Group as a Thrombotic Risk Factor in Children With Acute Lymphoblastic Leukemia: A Retrospective Study of 523 Patients. J Pediatr Hematol Oncol 2015; 37: e328-e332.

Baudouy D, Moceri P, Chiche O, Bouvier P, Schouver ED, Cerboni P, et al. B blood group: A strong risk factor for venous thromboembolism recurrence. Thromb Res 2015; 136: 107-111.

Dentali F, Di Minno MN, Turato S, Crestani S, Ambrosino P, Bonfanti C, et al. Role of ABO blood group and of other risk factors on the presence of residual vein obstruction after deep-vein thrombosis. Thromb Res 2014; 134: 264-267.

Ohira T, Cushman M, Tsai MY, Zhang Y, Heckbert SR, Zakai NA, et al. ABO blood group, other risk factors and incidence of venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE). J Thromb Haemost 2007; 5: 1455-1461.


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