Determinants of quality of life as measured with variants of SF-36 in patients with predialysis chronic kidney disease
Methods: A systematic literature search was conducted for relevant observational studies published between April 2007 and April 2017 in MEDLINE, EBSCOhost, and CINAHL databases.
Results: Thirteen observational studies with a total sample of 8635 subjects comprising 53.3% male with an aggregate mean age of 59.5 (SD 14.9) years were included in this review. Of the 8 generic HRQOL domains of the Short-Form Health Surveys, Social Functioning had the highest mean score whereas General Health had the lowest mean score in patients with predialysis CKD. Physical component summary (PCS) was more impaired than mental component summary (MCS). The determinants of poor HRQOL in predialysis CKD patients included both modifiable risk factors such as comorbidities (namely anxiety and depression), low serum hemoglobin level, sedentary lifestyle, unemployment and non-modifiable risk factors such as poor glomerular filtration rate, female gender, and older age. The risk factors impeded PCS more than MCS.
Conclusion: Several risk factors influence HRQOL impairment in patients with predialysis CKD, with PCS being more impacted than MCS. The risk factors for poor HRQOL are important for future research and for improving renal care in patients with predialysis CKD.
Saudi Med J 2018; Vol. 39 (7): 653-661
How to cite this article:
Alhaji MM, Tan J, Hamid MR, Timbuak JA, Naing L, Tuah NA. Determinants of quality of life as measured with variants of SF-36 in patients with predialysis chronic kidney disease. Saudi Med J. 2018 Jul;39(7):653-661. doi: 10.15537/smj.2018.7.21352.
Hill NR, Fatoba ST, Oke JL, Hirst JA, O ’callaghan CA, Lasserson DS, et al. Global prevalence of chronic kidney disease. A systematic review and meta-analysis. PLoS One 2016; 11: 1-18.
Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, et al. Chronic kidney disease: Global dimension and perspectives. Lancet 2013; 382: 260-272.
Levin A, Tonelli M, Bonventre J, Coresh J, Donner JA, Fogo AB, et al. Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy. Lancet 2017; 6736: 1-30.
Lins L, Carvalho FM. SF-36 total score as a single measure of health-related quality of life: scoping review. SAGE Open Med 2016; 4: 2050312116671725.
Jesky MD, Dutton M, Dasgupta I, Yadav P, Ng KP, Fenton A, et al. Health-related quality of life impacts mortality but not progression to end-stage renal disease in pre-dialysis chronic kidney disease: a prospective observational study. PLoS One 2016; 11: e0165675.
Ware JE, Kosinski M. Interpreting SF-36 summary health measures: a response. Qual Life Res 2001; 10: 405-13-20.
Porter AC, Lash JP, Xie D, Pan Q, DeLuca J, Kanthety R, et al. Predictors and outcomes of health-related quality of life in adults with CKD. Clin J Am Soc Nephrol 2016; 11: 1154-1162.
Aggarwal HK, Jain D, Pawar S, Yadav RK. Health-related quality of life in different stages of chronic kidney disease. QJM 2016; 109: 711-716.
Chong K, Unruh M. Why does quality of life remain an under-investigated issue in chronic kidney disease and why is it rarely set as an outcome measure in trials in this population? Nephrol Dial Transplant 2017; 32 (Suppl 2): ii47-ii52.
Clarke AL, Yates T, Smith AC, Chilcot J. Patient’s perceptions of chronic kidney disease and their association with psychosocial and clinical outcomes: A narrative review. Clin Kidney J 2016; 9: 494-502.
Chen SS, Al Mawed S, Unruh M. Health-related quality of life in end-stage renal disease patients: how often should we ask and what do we do with the answer? Blood Purif 2016; 41: 218-224.
Manavalan M, Priyamvada PS, Majumdar A, Kumar KTH. Assessment of health-related quality of life and its determinants in patients with chronic kidney disease. Indian J Nephrol 2017; 27: 37-43.
Peters MDJ, Godfrey CM, Khalil H, McInerney P, Parker D, Soares CB. Guidance for conducting systematic scoping reviews. Int J Evid Based Health 2015; 13: 141-146.
Pearson A, Field J, Jordan Z. Appendix 3 data extraction tools. Evidence-Based Clin Pract Nurs Heal Care 2009; 183-186.
Joanna Briggs Institute. Critical Appraisal Tools. Available from: http://joannabriggs.org/research/critical-appraisal-tools.html
Leech NL, KC Barrett, GA M. IBM SPSS for intermediate statistics: Use and interpretation. 5th ed. Abingdon (UK): Routledge; 2014.
Simms RJ, Thong KM, Dworschak GC, Ong ACM. Increased psychosocial risk, depression and reduced quality of life living with autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 2016; 31: 1130-1140.
Ibrahim N, Aini Pakri Mohamed R, Teo S, Che Din N, Halim Abdul Gafor A, Ismail R, et al. Association between health-related quality of life and psychological distress at different stages of chronic kidney disease. Sains Malaysiana 2016; 45: 753-759.
Feng L, Yap KB, Ng TP. Depressive symptoms in older adults with chronic kidney disease: Mortality, quality of life outcomes, and correlates. Am J Geriatr Psychiatry 2013; 21: 570-579.
IBM Support. ANOVA with summary data [Internet]. 2016 [cited 2017 June 4]. Available from: http://www-01.ibm.com/support/docview.wss?uid=swg21476127
Mansur H, Colugnati FA, Grincenkov FR dos S, Bastos M. Frailty and quality of life: a cross-sectional study of Brazilian patients with pre-dialysis chronic kidney disease. Health Qual Life Outcomes 2014; 12: 27.
Lemos CF, Rodrigues MP, Paulo Veiga JR, Veiga JRP. Family income is associated with quality of life in patients with chronic kidney disease in the pre-dialysis phase: a cross sectional study. Heal Qual Life Outcomes 2015; 13: 1-9.
Moher D, Liberati A, Tetzlaff J, Altman DG, Altman D, Antes G, et al. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Med 2009. 6: e1000097.
Peng T, Hu Z, Guo L, Xia Q, Li D, Yang X. Relationship between psychiatric disorders and quality of life in nondialysis patients with chronic kidney disease. Am J Med Sci 2013; 345: 218-221.
Miskulin DC, Abebe KZ, Chapman AB, Perrone RD, Steinman TI, Torres VE, et al. Health-related quality of life in patients with autosomal dominant polycystic kidney disease and CKD stages 1-4: a cross-sectional study. Am J Kidney Dis 2014; 63: 214-226.
Delgado CEY, Jaramillo MM, Orozco BEO, Santaella MHC, Nunez JJY, Munoz JPL, et al. Quality of life in patients with chronic kidney disease without dialysis or transplant: a random sample from two insurance companies. Medellin, Colombia, 2008. Nefrologia 2009; 29: 548-556. [Spanish]
National Kidney Foundation. Clinical practice guidelines for chronic kidney disease: evaluation, clasification and stratification. American Journal of Kidney Diseases 2002; 39: 1-356.
Chin HJ, Song YR, Lee JJ, Lee SB, Kim KW, Na KY, et al. Moderately decreased renal function negatively affects the health-related quality of life among the elderly Korean population: A population-based study. Nephrol Dial Transplant 2008; 23: 2810-2817.
Mujais SK, Story K, Brouillette J, Takano T, Soroka S, Franek C, et al. Health-related quality of Life in CKD patients: Correlates and evolution over time. Clin J Am Soc Nephrol 2009; 4: 1293-1301.
Lee SJ, Jeon JH. Relationship between symptom clusters and quality of life in patients at stages 2 to 4 chronic kidney disease in Korea. Appl Nurs Res 2015; 28: e13-e19.
Qaseem A, Hopkins RH, Sweet DE, Starkey M, Shekelle P, EM B, et al. Screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease: a clinical practice guideline from the Clinical Guidelines Committee of the American College of Physicians. Ann Intern Med 2013; 157: 251-262.
Zimbudzi E, Lo C, Ranasinha S, Gallagher M, Fulcher G, Kerr PG, et al. Predictors of health-related quality of life in patients with co-morbid diabetes and chronic kidney disease. PLoS One 2016; 11: (12).
Liu WJ, Musa R, Chew TF, Lim CTS, Morad Z, Bujang A. Quality of life in dialysis: A Malaysian perspective. Hemodial Int 2014; 18: 495-506.
Tsai YC, Hung CC, Hwang SJ, Wang SL, Hsiao SM, Lin MY, et al. Quality of life predicts risks of end-stage renal disease and mortality in patients with chronic kidney disease. Nephrol Dial Transplant 2010; 25: 1621-1626.
McKercher C, Sanderson K, Jose MD. Psychosocial factors in people with chronic kidney disease prior to renal replacement therapy. Nephrology 2013; 18: 585-591.
Wang MTM, Bolland MJ, Grey A. Reporting of limitations of observational research. JAMA Intern Med 2015; 175: 1571-1157.
Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 2005; 5: 13.
- There are currently no refbacks.
Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention. Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.